Clinical Specialties : Interventional Neurology

Interventional Neurology Research

The Division of Interventional Neurology is conducting cutting edge research in Translational and Clinical Trial Studies in stroke:

Translational Research

The Translational focus is on intra-arterial delivery of stem cells for the treatment of acute and sub-acute stroke.

  1. Intra-arterial Mesenchymal Stem Cell Delivery in a Canine Model of Acute Ischemic Stroke
  2. Optimal Timing and Efficacy of Intravascular Mesenchymal Stem Cell Delivery in a Rodent Stroke Model

Clinical Trials in Acute Stroke

The Division of Interventional Neurology is conducting cutting edge research in Translational and Clinical Trial Studies in stroke. Our division is participating in ground breaking NIH and industry sponsored multi-center clinical trials in the interventional treatment of Acute Ischemic Stroke. The current trials include: RECOVER-Stroke, CRISP, SWIFT Prime, THERAPY, Separator 3D, MULTISTEM, RETROSTART, MCMIA, TREVO, MIAMIS, and Recanalization Rate Study.

The Division has presented several platform and poster presentations off the ongoing results of these studies at the International Stroke Conference and American Academy of Neurology meetings.

The RECOVER-Stroke trial was the first US clinical trial for patients in which we treat them with their own bone marrow stem cells within in two weeks of their stroke. These patients received direct catheter delivery of MSCs into the carotid artery, the main artery going to the brain. Our site quickly became the fastest enrolling site in the nation prior to the stopping of enrollment in January 2014 for interim analysis. MULTISTEM, our newest stem cell therapy trial, will be open for enrollment in the coming days.

http://www.wndu.com/mmm/headlines/Stem-Cells-and-Stroke-220707181.html

Research Support

Research in the Division of Interventional Neurology is supported by grant funding from Inter-Disciplinary Research Initiative (IDRI) at the University of Miami, the Anderson Family Gift Fund and Department of Neurology. The clinical trials are supported via industry funding and NIH sub-contracts. The Division encourages charitable contributions to further support our research efforts in this important area of stroke therapeutics.