Epilepsy Research

Epilepsy Research

The faculty of the ICE is actively involved in clinical research trials evaluating the efficacy and safety of important drugs. They have been involved in pivotal clinical research trials which have lead to the approval of nine new antiepileptic drugs in the past 14 years. Below is a list of current studies. Please click on the study description for more details.

Study Description Enrollment Status
Vertex-765 A Phase 2, Randomized, Double-blind, Placebo-controlled Study of VX-765 in Subjects With Treatment-resistant Partial Epilepsy Not Enrolling
Memantine Study Efficacy and Safety of the Use of Memantine for Preserving Cognition in Adult Patients with Epilepsy. Actively Enrollment
ASERT Assessment of Suicidality in Epilepsy-Rating Tools (ASERT) Actively Enrolling
Lamotrigine-IR vs. Lamotrigine-XR Determination of Relative and Absolute Bioavailability and Clearance of Lamotrigine-IR and Lamotrigine-XR by a Stable-Isotope Technique in Older Patients Closed
SP 615 A Open-Label, Extension Trial to Determine Tolerability and Efficacy of Long-Term Oral SPM 927 as Adjunctive Therapy in Patients with Partial Seizures (Incorporating Amendment 1 & 2) Protocol SP 615. Closed
Retigabine A multicenter, open-label, long term, safety, tolerability and efficacy study of retigabine in adult epilepsy patients with partial-onset seizures (Extension of STudy VRXspan class=“caps”>RET-E22-301) VRXRET-E22-303 Not Enrolling